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MMPI-1154
$300 – $2,800
Products Details
Product Description
– MMPI-1154 is a promising novel cardio-cytoprotective imidazole-carboxylic acid (ICA) MMP-2 inhibitor(IC50=6.6 μM) and can be used for the study of acute myocardial infarction. MMPI-1154 also inhibits the activity of MMP-13, MMP-1 and MMP-9 with IC50s of 1.8 μM,10 μM, and 13 μM, respectively[1].
Web ID
– HY-117970
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C26H24FN3O3
References
Р[1]P̩ter Bencsik, et al. Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection.Front Pharmacol. 2018 Apr 5;9:296.
CAS Number
– 1382722-47-5
Molecular Weight
– 445.49
Compound Purity
– 99.87
SMILES
– O=C(C1=CN=C(CN(CC2=CC=C(F)C=C2)CC3=CC=C(OCC4=CC=CC=C4)C=C3)N1)O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– MMP
Isoform
– MMP-1;MMP-13;MMP-2;MMP-9
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
