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Products Details
Product Description
– MMP145 (compound 27) is a potent, selective and orally active MMP-12 inhibitor. MMP145 is effective in inflammation and asthma reasearch[1].
Web ID
– HY-14155
Shipping
– Room temperature
Molecular Formula
– C20H20N2O7S
References
– [1]Wei Li,Jianchang Li,Yuchuan Wu,Fabio Rancati,Stefania Vallese,Luca Raveglia ,Junjun Wu ,Rajeev Hotchandani,Nathan Fuller,Kristina Cunningham ,Paul Morgan ,Susan Fish,Rustem Krykbaev , Xin Xu , Steve Tam , Samuel J. Goldman , William Abraham , Cara Williams,Joseph Sypek and Tarek S.Mansour.Identification of an Orally Efficacious Matrix Metalloprotease 12 Inhibitor for Potential Treatment of AsthmaJ. Med. Chem., 2009, 52 (17), pp 5408–5419.|[2]Li W, et, al. Identification of an orally efficacious matrix metalloprotease 12 inhibitor for potential treatment of asthma. J Med Chem. 2009 Sep 10;52(17):5408-19.
CAS Number
– 1025717-75-2
Molecular Weight
– 432.45
SMILES
– CC(C)[C@@H](C(O)=O)NS(=O)(C1=CC=C(C2=CC(N3C(OCC3)=O)=CC=C2O4)C4=C1)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– MMP
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
