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Products Details
Product Description
– MMP13-IN-5 (compound 13m) is a potent and selective inhibitor of MMP-2/MMP-13 (IC50=3.6 μM/14.6 μM)，involved in osteoarthritis (OA)[1].
Web ID
– HY-149378
Shipping
– Room temperature
Molecular Formula
– C22H18BrN3O5
References
– [1]Cuffaro D, et al. Identification of N-Acyl Hydrazones as New Non-Zinc-Binding MMP-13 Inhibitors by Structure-Based Virtual Screening Studies and Chemical Optimization. Int J Mol Sci. 2023 Jul 4;24(13):11098.
Molecular Weight
– 484.30
SMILES
– O=C(N/N=C/C1=CC=C(CNC(C2=CC=C(Br)O2)=O)C=C1)CC3=CC=C(C(O)=O)C=C3
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– MMP
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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