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MMP-7-IN-1
$650 – $4,750
Products Details
Product Description
– MMP-7-IN-1 is a potent and selective inhibitor of MMP-7 over MMP-1, -2, -3, -8, -9, -13 with an IC50 value of 10 nM. MMP-7 is a potential target for diseases including cancer and fibrosis[1].
Web ID
– HY-151540
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C31H44ClF3N6O9S
References
– [1]Tabuse H, et al. Discovery of Highly Potent and Selective Matrix Metalloproteinase-7 Inhibitors by Hybridizing the S1′ Subsite Binder with Short Peptides. J Med Chem. 2022 Oct 13;65(19):13253-13263.
CAS Number
– 2865097-05-6
Molecular Weight
– 769.23
Compound Purity
– 99.68
SMILES
– ClC1=CC=C(C=C1C(F)(F)F)S(N[C@@H](CCC(NCC(N[C@H](C(N[C@H](C(N2CCC[C@H]2CC(N)=O)=O)C(C)C)=O)CC(C)C)=O)=O)C(O)=O)(=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– MMP
Isoform
– MMP-7
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.