Products Details

Product Description

– MMP-13-IN-1 is a potent and selective inhibitor of MMP-13 with a IC50 value of 16 nM. MMP-13-in-1 can be used for atherosclerosis research[1].

Web ID

– HY-154868

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C19H16F3N3O3

References

– [1]Buchler A, et al. Quinazoline-2-Carboxamides as Selective PET Radiotracers for Matrix Metalloproteinase-13 Imaging in Atherosclerosis. J Med Chem. 2023 May 25;66(10):6682-6696.

CAS Number

– 2925249-49-4

Molecular Weight

– 391.34

SMILES

– FC(C(C)=C1)=CC=C1CNC(C2=NC3=C(C(N2)=O)C(OCCF)=C(C=C3)F)=O

Clinical Information

– No Development Reported

Research Area

– Cancer; Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– MMP

Isoform

– MMP-13

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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