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MMAD
$80 – $450
Products Details
Product Description
– MMAD is a potent tubulin inhibitor, is a toxin payload in antibody agent conjugates (ADCs).
Web ID
– HY-15581
Storage Temperature
– 4°C (Powder, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C41H66N6O6S
References
– [1]Chudasama V, et al. Recent advances in the construction of antibody-drug conjugates. Nat Chem. 2016 Feb;8(2):114-9.
CAS Number
– 203849-91-6
Molecular Weight
– 771.06
Compound Purity
– 99.94
SMILES
– O=C([C@H](C)[C@H]([C@]1([H])CCCN1C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C([C@@H](NC([C@@H](N(C)[H])C(C)C)=O)C(C)C)=O)C)=O)OC)N[C@@H](CC2=CC=CC=C2)C3=NC=CS3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 24.5 mg/mL (ultrasonic;warming)
Target
– ADC Cytotoxin;Microtubule/Tubulin
Isoform
– Auristatin
Pathway
– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
