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ML314
$144 – $840
Products Details
Product Description
– ML314 is a potent molecule agonist of NTR1 (EC50 = 1.9 μM); showed good selectivity against NTR2 and GPR35, but does not stimulate Ca2+ mobilization.
Web ID
– HY-16639
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C24H28N4O3
References
– [1]Hershberger P, et al. Small Molecule Agonists for the Neurotensin 1 Receptor (NTR1 Agonists). Probe Reports from the NIH Molecular Libraries Program
CAS Number
– 1448895-09-7
Molecular Weight
– 420.50
Compound Purity
– 99.82
SMILES
– COC1=CC=CC=C1N2CCN(C3=C4C=C(OC)C(OC)=CC4=NC(C5CC5)=N3)CC2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Endocrinology
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– GPR35 ;Neurotensin Receptor
Isoform
– NTR1
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
