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ML311
$47 – $960
Products Details
Product Description
– ML311 is a potent and selective inhibitor of the Mcl-1/Bim interaction.
Web ID
– HY-101778
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H24F3N3O
References
– [1]Bannister T, et al. ML311: A Small Molecule that Potently and Selectively Disrupts the Protein-Protein Interaction of Mcl-1 and Bim: A Probe for Studying Lymphoid Tumorigenesis. Biotechnology Information (US); 2010-2012 Apr 16.
CAS Number
– 315698-17-0
Molecular Weight
– 415.45
Compound Purity
– 98.26
SMILES
– OC1=C2N=CC=CC2=CC=C1C(N3CCN(CC)CC3)C4=CC=C(C(F)(F)F)C=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 67.5 mg/mL (ultrasonic)
Target
– Bcl-2 Family
Isoform
– Bim;Mcl-1
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
