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ML167

$92$515

Products Details

Product Description

– ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, >10-fold selectivity for closely related kinases Clk1, Clk2, Clk3 and Dyrk1A/1B[1].

Web ID

– HY-15951

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C19H17N3O3

References

– [1]Rosenthal AS, et al. An inhibitor of the Cdc2-like kinase 4 (Clk4).

CAS Number

– 1285702-20-6

Molecular Weight

– 335.36

Compound Purity

– 98.62

SMILES

– OCC1=CC=C(C2=CC3=C(NCC4=CC=C(C)O4)N=CN=C3C=C2)O1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 16.67 mg/mL (ultrasonic)

Target

– CDK;DYRK

Isoform

– CDK3;CLK;DYRK1

Pathway

– Cell Cycle/DNA Damage;Protein Tyrosine Kinase/RTK

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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