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ML-226
SKU
HY-129121-Get quote
Category Reference compound
Tags MAGL, Metabolic Enzyme/Protease, Neurological Disease
Products Details
Product Description
– ML226 is a potent α/β hydrolase domain-containing protein 11 (ABHD11) inhibitor in vitro and in situ with IC50s of 15 and 0.68 nM, respectively[1].
Web ID
– HY-129121
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C23H26N4O2
References
– [1]Hsu KL, et al. Optimization and characterization of triazole urea inhibitors for abhydrolase domain containing protein 6 (ABHD6). 2012 Apr 12 [updated 2013 Mar 14]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.
CAS Number
– 2055172-43-3
Molecular Weight
– 390.48
SMILES
– O=C(N1C(CC)CCCC1)N2N=CC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)=N2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– MAGL
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.