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Mivotilate
SKU
HY-100242-10 mg
Category Reference compound
Tags Aryl Hydrocarbon Receptor, Immunology/Inflammation, Others
$300 – $2,250
Products Details
Product Description
– Mivotilate is a nontoxic, potent activator of the aryl hydrocarbon receptor (AhR), and acts as a hepatoprotective agent.
Web ID
– HY-100242
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C12H14N2O3S3
References
– [1]Whelan F, et al. Amino acid substitutions in the aryl hydrocarbon receptor ligand binding domain reveal YH439 as an atypical AhR activator. Mol Pharmacol. 2010 Jun;77(6):1037-46.|[2]Jeong KS, et al. Transcriptional inhibition of cytochrome P4502E1 by a synthetic compound, YH439. Arch Biochem Biophys. 1996 Feb 1;326(1):137-44.|[3]Lee IJ, et al. Transcriptional induction of the cytochrome P4501A1 gene by a thiazolium compound, YH439. Mol Pharmacol. 1996 Jun;49(6):980-8.
CAS Number
– 130112-42-4
Molecular Weight
– 330.45
Compound Purity
– 99.58
SMILES
– O=C(OC(C)C)/C(C(NC1=NC(C)=CS1)=O)=C2SCS2
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Aryl Hydrocarbon Receptor
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.