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MitoBloCK-6
$95 – $250
Products Details
Product Description
– MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce apoptosis via cytochrome c release in hESCs[1].
Web ID
– HY-122652
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C19H14Cl2N2O
References
– [1]Dabir DV, et, al. A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Dev Cell. 2013 Apr 15;25(1):81-92.
CAS Number
– 303215-67-0
Molecular Weight
– 357.23
Compound Purity
– 98.07
SMILES
– OC1=C(/C=N/C2=CC=C(NC3=CC=CC=C3)C=C2)C=C(Cl)C=C1Cl
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic;warming)
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.