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Miravirsen
SKU
HY-132598-10 mg
Category Oligonucleotides
Tags Anti-infection;Epigenetics, HCV;MicroRNA, Infection; Inflammation/Immunology
$800 – $1,300
Products Details
Product Description
– Miravirsen (SPC-3649) is a potent miR-122 inhibitor and inhibits the biogenesis of miR-122. Miravirsen is a 15-nucleotide locked nucleic acid-modified phosphorothioate antisense oligonucleotide. Miravirsen inhibits HCV replication. Miravirsen can be used in research of HCV infection[1][2].
Web ID
– HY-132598
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– N/A
References
– [1]Elmén J, et, al. Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver. Nucleic Acids Res. 2008 Mar;36(4):1153-62.|[2]Luca F R Gebert, et al. Miravirsen (SPC3649) can inhibit the biogenesis of miR-122. Nucleic Acids Res. 2014 Jan;42(1):609-21.
CAS Number
– 1072874-90-8
Molecular Weight
– 4967.00
Compound Purity
– 98.0
SMILES
– [Miravirsen]
Clinical Information
– Phase 2
Research Area
– Infection; Inflammation/Immunology
Solubility
– H2O : 100 mg/mL (ultrasonic)
Target
– HCV;MicroRNA
Pathway
– Anti-infection;Epigenetics
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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