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Products Details
Product Description
– Mipomersen (ISIS 301012 free base) is an antisense oligonucleotide inhibitor of apolipoprotein B (apoB). Mipomersen has anti-HCV effect and reduces the infectivity of the HCV. Mipomersen can be used for the research of homozygous familial hypercholesterolemia (HoFH)[1][2].
Web ID
– HY-148647
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C230H324N67O122P19S19
References
– [1]Merki E, et al. Antisense oligonucleotide directed to human apolipoprotein B-100 reduces lipoprotein(a) levels and oxidized phospholipids on human apolipoprotein B-100 particles in lipoprotein(a) transgenic mice. Circulation. 2008 Aug 12;118(7):743-53.|[2]Schaefer EA, et al. Apolipoprotein B100 is required for hepatitis C infectivity and Mipomersen inhibits hepatitis C. World J Gastroenterol. 2016 Dec 7;22(45):9954-9965.
CAS Number
– 1000120-98-8
Molecular Weight
– 7177.00
SMILES
– [Mipomersen]
Clinical Information
– Launched
Research Area
– Infection
Solubility
– H2O : ≥ 100 mg/mL
Target
– HCV
Pathway
– Anti-infection
Product type
– Oligonucleotides
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
