Download Files:
Mimosine
$30 – $50
Products Details
Product Description
– Mimosine, a tyrosine analog , can act as an antioxidant by its potent iron-binding activity[1]. Mimosine is a known chelator of Fe(III)[2]. Mimosine induces apoptosis through metal ion chelation, mitochondrial activation and ROS production in human leukemic cells[3]. Anti-cancer, antiinflammation.
Web ID
– HY-N0928
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C8H10N2O4
References
– [1]Keiko Murakami, et al. Generation of reactive oxygen species by hydroxypyridone compound/iron complexes. Redox Rep. 2020 Dec;25(1):59-63.|[2] Michael D H Honda, et al. Mimosine facilitates metallic cation uptake by plants through formation of mimosine-cation complexes.Plant Mol Biol. 2020 Mar;102(4-5):431-445.|[3]MaherHallakMSc, et al. Mimosine Induces Apoptosis through Metal Ion Chelation, Mitochondrial Activation and Reactive Oxygen Species Production in Human Leukemic Cells. Blood.2004, Nov 16, 104 (11): 4481.|[4]K S Kulp, et al. Mimosine blocks cell cycle progression by chelating iron in asynchronous human breast cancer cells. Toxicol Appl Pharmacol. 1996 Aug;139(2):356-64.|[5]Pipatpong Kanla, et al. Acute Effects of Mimosine Purified from <i>Leucaena leucocephala</i> on Male Reproductive System of Adult Mice. Int. J. Morphol., 36(2):507-512, 2018.
CAS Number
– 500-44-7
Molecular Weight
– 198.18
Compound Purity
– 99.21
SMILES
– OC([C@@H](N)CN1C=CC(C(O)=C1)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– H2O : 5 mg/mL (ultrasonic;warming;adjust pH to 2 with HCl;heat to 60°C)
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
