Download Files:
Miglustat (hydrochloride)
$100 – $1,050
Products Details
Product Description
– Miglustat (N-Butyldeoxynojirimycin) hydrochloride is an orally active and reversible ceramide glucosyltransferase inhibitor. Miglustat hydrochloride can be used for the research of type I gaucher disease[1][2].
Web ID
– HY-17020A
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C10H22ClNO4
Citations
– Cell. 2019 Dec 12;179(7):1483-1498.e22.|Cell Rep. 2022 Jul 5;40(1):111049.
References
– [1]Maria Cristina Dechecchi, et al. Anti-inflammatory effect of miglustat in bronchial epithelial cells. J Cyst Fibros. 2008 Nov;7(6):555-65. |[2]G D’Arcangelo, et al. Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease. Neural Plast. 2016:2016:3830424.
CAS Number
– 210110-90-0
Molecular Weight
– 255.74
Compound Purity
– 98.20
SMILES
– O[C@H]1[C@H](O)[C@@H](CO)N(CCCC)C[C@@H]1O.[H]Cl
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– DMSO : 65 mg/mL (ultrasonic)|H2O : ≥ 34 mg/mL
Target
– Glucosylceramide Synthase (GCS)
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
