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Miglustat
$110 – $520
Products Details
Product Description
– Miglustat (N-Butyldeoxynojirimycin) is an orally active and reversible ceramide glucosyltransferase inhibitor. Miglustat can be used for the research of type I gaucher disease[1].
Web ID
– HY-17020
Storage Temperature
– 4°C (Powder, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C10H21NO4
Citations
– Cell Rep. 2022 Jul 5;40(1):111049.|Cell. 2019 Dec 12;179(7):1483-1498.e22.
References
– [1]Maria Cristina Dechecchi, et al. Anti-inflammatory effect of miglustat in bronchial epithelial cells. J Cyst Fibros. 2008 Nov;7(6):555-65. |[2]G D’Arcangelo, et al. Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease. Neural Plast. 2016:2016:3830424.
CAS Number
– 72599-27-0
Molecular Weight
– 219.28
Compound Purity
– 98.0
SMILES
– O[C@H]1[C@H](O)[C@@H](CO)N(CCCC)C[C@@H]1O
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– H2O : 250 mg/mL (ultrasonic)
Target
– Glucosylceramide Synthase (GCS)
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
