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Products Details
Product Description
– MIF-IN-5 (compound 1d) is a potent and reversible macrophage migration inhibitory factor (MIF) competitive inhibitor with an IC50 of 4.8 μM and a Ki value of 3.3 μM, respectively[1].
Web ID
– HY-146318
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C18H14FN5O2
References
– [1]Xiao Z, Fokkens M, Chen D, et al. Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem. 2020;186:111849.
CAS Number
– 2582755-31-3
Molecular Weight
– 351.33
SMILES
– O=C(NCC1=CN(N=N1)C2=CC(F)=C(C=C2)O)C3=CC4=CC=CC=C4N3
Clinical Information
– No Development Reported
Research Area
– Cancer; Metabolic Disease; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Macrophage migration inhibitory factor (MIF)
Pathway
– Immunology/Inflammation
Product type
– Reference compound
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