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Midaglizole
$400 – $3,400
Products Details
Product Description
– Midaglizole ((±)-DG5128 free base; DG5128 free base) is a potent α2-adrenoceptor antagonist. Midaglizole is a hypoglycemic agent. Midaglizole increases blood pressure and reduces blood glucose levels in vivo[1][2][3].
Web ID
– HY-148529
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Molecular Formula
– C16H17N3
References
– [1]Hirohashi M, et al. Intrinsic pressor activity of midaglizole, an alpha-2 adrenoceptor antagonist, in pithed rats. Jpn J Pharmacol. 1990 Aug;53(4):519-20. |[2]Ohneda K, et al. Mechanism of insulin secretion by midaglizole. Diabetes Res Clin Pract. 1993 Feb;19(2):127-32.|[3]Proks P, et al. Inhibition of recombinant K(ATP) channels by the antidiabetic agents midaglizole, LY397364 and LY389382. Eur J Pharmacol. 2002 Sep 27;452(1):11-9.
CAS Number
– 66529-17-7
Molecular Weight
– 251.33
Compound Purity
– 98.28
SMILES
– C1(C(C2=CC=CC=C2)CC3=NCCN3)=NC=CC=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 162.5 mg/mL (ultrasonic)
Target
– Adrenergic Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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