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Products Details
Product Description
– Microtubule stabilizing agent-1 (compound 3l) is a Paclitaxel derivative that efficiently promotes tubulin polymerization. Microtubule stabilizing agent-1 shows antitumor efficacy[1].
Web ID
– HY-155647
Shipping
– Room temperature
Molecular Formula
– C45H55NO13
References
– [1]Yuntao Ma, et al. Modulation of taxane binding to tubulin curved and straight conformations by systematic 3’N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency. Eur J Med Chem. 2023 Nov 5;259:115668.
Molecular Weight
– 817.92
SMILES
– O[C@@H]1C(C2(C)C)=C([C@H](C[C@]2([C@H](C3[C@](C)(C1=O)[C@H](C[C@@H]4[C@@]3(OC(C)=O)CO4)O)OC(C5=CC=CC=C5)=O)O)OC([C@@H]([C@H](C6=CC=CC=C6)NC(/C=C/C(C)(C)C)=O)O)=O)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
