Download Files:
Microtubule inhibitor 6
SKU
HY-147727-Get quote
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;Cytoskeleton, Microtubule/Tubulin
Products Details
Product Description
– Microtubule inhibitor 6 (compound 17o) is a potent microtubule inhibitor. Microtubule inhibitor 6 shows cytotoxicity with IC50s of 14.0, 6.6, 7.0 nM for NCI-H460, BxPC-3, HT-29 cells, respectively. Microtubule inhibitor 6 efficiently inhibits microtubule polymerization[1].
Web ID
– HY-147727
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H19FN2O5
References
– [1]Ding Z, et al. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer. Bioorg Med Chem. 2020 May 15;28(10):115435.
CAS Number
– 2416338-64-0
Molecular Weight
– 434.42
SMILES
– COCC1=CC=C(O1)/C=C2NC(/C(NC2=O)=C/C3=CC(OC4=CC=C(C=C4)F)=CC=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.