Products Details

Product Description

– Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity, with an IC50 value of 9-16 nM in cancer cells[1].

Web ID

– HY-114313

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C21H19NO3

References

– [1]Li W, et al. Discovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity. J Med Chem. 2019 Jan 24;62(2):993-1013.

CAS Number

– 2305668-80-6

Molecular Weight

– 333.38

SMILES

– O=C(C1=CC(C)=NC2=CC=CC=C12)/C(C)=C/C3=CC=C(OC)C(O)=C3

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Microtubule/Tubulin

Pathway

– Cell Cycle/DNA Damage;Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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