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Products Details
Product Description
– microRNA-21-IN-1 (compound 7A) is an efficient microRNA inhibitor. microRNA-21-IN-1 has antiproliferative activity against Hela and HCT-116 cells with IC50s of 5.5 μM and 2.8 μM respectively, as well as promotes apoptosis of Hela cells. microRNA-21-IN-1 upregulates the expression of microRNA-21 downstream functional targets (PTEN, EGR1 and SLIT2). microRNA-21-IN-1 can be used for researching anticancer[1].
Web ID
– HY-146411
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C30H37FN6O3
References
– [1]Xi XX, et al. Identification of benzamides derivatives of norfloxacin as promising microRNA-21 inhibitors via repressing its transcription. Bioorg Med Chem. 2022;66:116803.
CAS Number
– 2848720-31-8
Molecular Weight
– 548.65
SMILES
– CCN1C=C(C(C2=CC(F)=C(C=C21)N3CCNCC3)=O)C(NC4=CC=C(C=C4)C(NCCN5CCCCC5)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;MicroRNA
Pathway
– Apoptosis;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
