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Products Details
Product Description
– Microcystin-LY, a cyclic heptapeptide toxin from the cyanobacterium Microcystis aeruginosa[2], acts as an activator of the Nrf2 pathway to induce oxidative stress response, and the induction effect is most obvious at 3μM.[1].
Web ID
– HY-N11682
Shipping
– Room temperature
Molecular Formula
– C52H71N7O13
References
– [1]Lundqvist J, et al. Microcystins activate nuclear factor erythroid 2-related factor 2 (Nrf2) in human liver cells in vitro – Implications for an oxidative stress induction by microcystins. Toxicon. 2017 Feb;126:47-50.|[2]Stoner RD, et al. The effects of single L-amino acid substitutions on the lethal potencies of the microcystins. Toxicon. 1989;27(7):825-8.
CAS Number
– 123304-10-9
Molecular Weight
– 1002.16
SMILES
– O=C(N[C@H]([C@@H](C(N[C@H](CCC(N(C1=C)C)=O)C(O)=O)=O)C)/C=C/C(C)=C/[C@H](C)[C@@H](OC)CC2=CC=CC=C2)[C@@H](NC([C@H]([C@@H](NC([C@@H](NC([C@H](NC1=O)C)=O)CC(C)C)=O)C(O)=O)C)=O)CC(C=C3)=CC=C3O
Clinical Information
– No Development Reported
Research Area
– others
Solubility
– 10 mM in DMSO
Target
– Keap1-Nrf2
Pathway
– NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
