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Mibampator
$310 – $1,800
Products Details
Product Description
– Mibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors.
Web ID
– HY-10934
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H30N2O4S2
References
– [1]Zmijewski M, et al. Application of biocatalysis to drug metabolism: preparation of mammalian metabolites of a biaryl-bis-sulfonamide AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor potentiator using Actinoplanes missouriensis. Drug Metab Dispos. 2006 Jun;34(6):925-31.|[2]Jones N, et al. AMPA receptor potentiation can prevent ethanol-induced intoxication. Neuropsychopharmacology. 2008 Jun;33(7):1713-23.
CAS Number
– 375345-95-2
Molecular Weight
– 438.60
Compound Purity
– 99.86
SMILES
– C[C@@H](CNS(C(C)C)(=O)=O)C1=CC=C(C2=CC=C(CCNS(C)(=O)=O)C=C2)C=C1
Clinical Information
– Phase 2
Research Area
– Neurological Disease
Solubility
– DMSO : ≥ 25 mg/mL
Target
– iGluR
Isoform
– AMPA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
