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Products Details
Product Description
– Mianserin-d3 (hydrochloride) is the deuterium labeled Mianserin hydrochloride. Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.
Web ID
– HY-B0188AS
Shipping
– Room temperature
Molecular Formula
– C18H18D3ClN2
References
– [1]Olianas MC,et al. The atypical antidepressant mianserin exhibits agonist activity at κ-opioid receptors. Br J Pharmacol. 2012 Nov;167(6):1329-41.|[2]Roeder T. High-affinity antagonists of the locust neuronal octopamine receptor. Eur J Pharmacol. 1990 Nov 27;191(2):221-4.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1219804-97-3
Molecular Weight
– 303.84
SMILES
– [2H]C([2H])([2H])N1CC2N(CC1)C3=CC=CC=C3CC4=CC=CC=C42.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Histamine Receptor;Isotope-Labeled Compounds
Isoform
– H1 Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
