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MI-3
$172 – $1,188
Products Details
Product Description
– MI-3 (Menin-MLL inhibitor 3) is a potent and high affinity menin-MLL inhibitor with an IC50 of 648 nM and a Kd of 201 nM[1].
Web ID
– HY-15223
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H25N5S2
References
– [1]Grembecka J, et al. Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia. Nature Chemical Biology (2012), 8(3), 277-284.
CAS Number
– 1271738-59-0
Molecular Weight
– 375.55
Compound Purity
– 99.51
SMILES
– CC(C)C1=CC2=C(N3CCN(C4=NCC(C)(C)S4)CC3)N=CN=C2S1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 8.33 mg/mL (ultrasonic)
Target
– Apoptosis;Epigenetic Reader Domain
Pathway
– Apoptosis;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
