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Products Details
Product Description
– MHJ-627 is a potent ERK5 (MAPK7) inhibitor (IC50: 0.91 μM). MHJ-627 promotes the mRNA expression of tumor suppressors and anti-metastatic genes, and promotes cancer cell death[1].
Web ID
– HY-149412
Shipping
– Room temperature
Molecular Formula
– C34H45BrN2O3
References
– [1]Hwang J, et al. Identification of a Novel ERK5 (MAPK7) Inhibitor, MHJ-627, and Verification of Its Potent Anticancer Efficacy in Cervical Cancer HeLa Cells. Curr Issues Mol Biol. 2023 Jul 24;45(7):6154-6169.
Molecular Weight
– 609.64
SMILES
– O=C(C[N+]1=CN(CCC(C)C)C2=C1C=CC=C2)C3=C(OCCC(C)C)C4=CC=CC=C4C(OCCC(C)C)=C3.[Br-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ERK
Isoform
– ERK5
Pathway
– MAPK/ERK Pathway;Stem Cell/Wnt
Product type
– Reference compound
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