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Products Details
Product Description
– mGlu4 receptor agonist 1 (compound 62) is a potent mGlu4 receptor positive allosteric modulator, with an EC50 of 308 nM. mGlu4 receptor agonist 1 shows significant anxiolytic- and antipsychotic-like effect[1].
Web ID
– HY-144698
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H15ClN4O2
References
– [1]Stankiewicz A, et al. New 1,2,4-oxadiazole derivatives with positive mGlu4 receptor modulation activity and antipsychotic-like properties. J Enzyme Inhib Med Chem. 2022 Dec;37(1):211-225.
CAS Number
– 1678501-16-0
Molecular Weight
– 390.82
SMILES
– CC1=CC(NC(C2=CC=CC=N2)=O)=CC=C1C3=NOC(C4=C(C=CC=C4)Cl)=N3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mGluR
Isoform
– mGluR4
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
