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MF-438

$130$1,815

Products Details

Product Description

– MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an IC50 of 2.3 nM for rSCD1[1].

Web ID

– HY-15822

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C19H18F3N5OS

References

Р[1]L̩ger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502.

CAS Number

– 921605-87-0

Molecular Weight

– 421.44

Compound Purity

– 99.92

SMILES

– FC(C1=CC=CC=C1OC2CCN(C3=NN=C(C4=NN=C(C)S4)C=C3)CC2)(F)F

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– DMF : 50 mg/mL (ultrasonic)|DMSO : 25 mg/mL (ultrasonic)

Target

– Stearoyl-CoA Desaturase (SCD)

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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