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MF-438
SKU
HY-15822-1 mg
Category Reference compound
Tags Metabolic Disease, Metabolic Enzyme/Protease, Stearoyl-CoA Desaturase (SCD)
$130 – $1,815
Products Details
Product Description
– MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an IC50 of 2.3 nM for rSCD1[1].
Web ID
– HY-15822
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C19H18F3N5OS
References
– [1]Léger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502.
CAS Number
– 921605-87-0
Molecular Weight
– 421.44
Compound Purity
– 99.92
SMILES
– FC(C1=CC=CC=C1OC2CCN(C3=NN=C(C4=NN=C(C)S4)C=C3)CC2)(F)F
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMF : 50 mg/mL (ultrasonic)|DMSO : 25 mg/mL (ultrasonic)
Target
– Stearoyl-CoA Desaturase (SCD)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.