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Products Details
Product Description
– METTL3-IN-2 (compound 28) is a METTL3 inhibitor with an IC50 value of 6.1 nM. METTL3-IN-2 inhibits cell proliferation of Caov3 cancer cells[1].
Web ID
– HY-148468
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H26N8O
References
– [1]Hardick, DJ, et al. Preparation of heteroaromatic compounds as METTL3 inhibitory compounds. WO2022074379. 2022.
CAS Number
– 2767258-88-6
Molecular Weight
– 454.53
SMILES
– COC1=CN2C(C(C3=CN(CC4=CN5C(C=CC(CNCC6(C7)CC7C6)=C5)=N4)N=N3)=C1)=CN=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– METTL3
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
