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Product Description
– Metronidazole hydrochloride (SC 326421) is an orally active nitroimidazole antibiotic, can be used to research anaerobic infections. Metronidazole hydrochloride can cross blood brain barrier and results inflammation and skeletal muscle contraction under long-term application[1][2][3][4].
Web ID
– HY-B0318A
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C6H10ClN3O3
References
– [1]Scully BE. Metronidazole. Med Clin North Am. 1988 May;72(3):613-21.|[2]Dhurga DB, et al. Granular Formation during Apoptosis in Blastocystis sp. Exposed to Metronidazole (MTZ). PLoS One. 2016 Jul 29;11(7):e0155390.|[3]Chaturvedi S, et al. Mechanistic exploration of quercetin against metronidazole induced neurotoxicity in rats: Possible role of nitric oxide isoforms and inflammatory cytokines. Neurotoxicology. 2020 Jul;79:1-10.|[4]Manickam R, et al. Metronidazole Causes Skeletal Muscle Atrophy and Modulates Muscle Chronometabolism. Int J Mol Sci. 2018 Aug 16;19(8):2418.
CAS Number
– 69198-10-3
Molecular Weight
– 207.61
SMILES
– OCCN1C([N+]([O-])=O)=CN=C1C.[H]Cl
Clinical Information
– Launched
Research Area
– Infection; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Apoptosis;Bacterial;Parasite
Pathway
– Anti-infection;Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
