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Metoprolol (succinate)
$92 – $502
Products Details
Product Description
– Metoprolol succinate is an orally active, selective β1-adrenoceptor antagonist. Metoprolol succinate shows anti-inflammation, antitumor and anti-angiogenic properties[1][2][3].
Web ID
– HY-17503A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C34H56N2O10
Citations
– J Pharmacol Sci. 2020 Sep;144(1):30-42.|Chemosphere. 2019 Jun;225:378-387. |Clin Pharmacol Ther. 2023 Nov 16.|Environ Toxicol. 2023 Dec 2.|J Chromatogr B. 2023 Jun 20, 123804.|J Pharmaceut Biomed. 2020, 113870.|Preprints. 2023 Jun 19.
References
– [1]Ulleryd MA, et al. Metoprolol reduces proinflammatory cytokines and atherosclerosis in ApoE-/- mice. Biomed Res Int. 2014;2014:548783.|[2]Wang D, et al. Carvedilol has stronger anti-inflammation and anti-virus effects than metoprolol in murine model with coxsackievirus B3-induced viral myocarditis. Gene. 2014 Sep 1;547(2):195-201.|[3]Hajatbeigi B, et al. Cytotoxicity of Metoprolol on Leukemic Cells in Vitro. IJBC 2018; 10(4): 124-129.|[4]Su Q, et al. Effect of metoprolol on myocardial apoptosis and caspase-9 activation after coronary microembolization in rats. Exp Clin Cardiol. 2013 Spring;18(2):161-5.
CAS Number
– 98418-47-4
Molecular Weight
– 652.82
Compound Purity
– 99.90
SMILES
– OC(CNC(C)C)COC1=CC=C(CCOC)C=C1.OC(CNC(C)C)COC2=CC=C(CCOC)C=C2.OC(CCC(O)=O)=O
Clinical Information
– Launched
Research Area
– Cardiovascular Disease; Endocrinology; Cancer
Solubility
– DMSO : 16.67 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL
Target
– Adrenergic Receptor;Apoptosis
Isoform
– β adrenergic receptor
Pathway
– Apoptosis;GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
