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Products Details
Product Description
– Metoprolol-d6 (tartrate) is the deuterium labeled Metoprolol tartrate. Metoprolol is an orally active, selective β1-adrenoceptor antagonist. Metoprolol shows anti-inflammation, antitumor and anti-angiogenic properties[1][2][3][4].
Web ID
– HY-17503BS
Shipping
– Room temperature
Molecular Formula
– C15H19D6NO3•1/2C4H6O6
References
– [1]Hajatbeigi B, et al. Cytotoxicity of Metoprolol on Leukemic Cells in Vitro. IJBC 2018; 10(4): 124-129.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[3]Ulleryd MA, et al. Metoprolol reduces proinflammatory cytokines and atherosclerosis in ApoE-/- mice. Biomed Res Int. 2014;2014:548783.|[4]Wang D, et al. Carvedilol has stronger anti-inflammation and anti-virus effects than metoprolol in murine model with coxsackievirus B3-induced viral myocarditis. Gene. 2014 Sep 1;547(2):195-201.
Molecular Weight
– 348.50
SMILES
– COCCC1=CC=C(C=C1)OCC(CNC(C([2H])([2H])[2H])C([2H])([2H])[2H])O.OC([C@@H]([C@H](C(O)=O)O)O)=O.[0.5]
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection; Endocrinology; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor;Isotope-Labeled Compounds
Isoform
– β adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
