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Methylnitronitrosoguanidine
$450
Only 1000 item(s) left in stock.
Products Details
Product Description
– Methylnitronitrosoguanidine (MNNG) is an orally active alkylating agent with toxic and mutagenic effects. Methylnitronitrosoguanidine can as a carcinogen and mutagen[1][2]. 50% water content, specifications are based on dry weight.
Web ID
– HY-128612
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C2H5N5O3
References
– [1]Slapikoff SA, et, al. Comparison of toxicity and mutagenicity of methylnitrosourea, methylnitronitrosoguanidine and ICR-191 among human lymphoblast lines. Mutat Res. 1980 May;70(3):365-71.|[2]Zhang L, Jia B, et, al. Corilagin induces apoptosis and inhibits HMBG1/PI3K/AKT signaling pathways in a rat model of gastric carcinogenesis induced by methylnitronitrosoguanidine. Environ Toxicol. 2022 May;37(5):1222-1230.
CAS Number
– 70-25-7
Molecular Weight
– 147.09
Compound Purity
– 99.91
SMILES
– N=C(N[N+]([O-])=O)N(C)N=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– DNA Alkylator/Crosslinker
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
