Methyldopate (hydrochloride)

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Products Details

Product Description

– Methyldopate hydrochloride is an ethyl ester hydrochloride proagent of α-Methyldopa (α-MD; HY-B0225). Methyldopa (L-(-)-α-Methyldopa) is an α-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopate hydrochloride has the potential for severe hypertension research[1].

Web ID

– HY-B1696A

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C12H18ClNO4

References

– [1]P D Walson, et al. Metabolic disposition and cardiovascular effects of methyldopate in unanesthetized rhesus monkeys. J Pharmacol Exp Ther. 1975 Oct;195(1):151-8.|[2]Hoskins JA, et al. Determination of alpha-methyldopa and methyldopate in human breast milk and plasma by ion-exchange chromatography using electrochemical detection. J Chromatogr. 1982 Jun 11;230(1):162-7.

CAS Number

– 2508-79-4

Molecular Weight

– 275.73

SMILES

– N[C@](CC1=CC=C(O)C(O)=C1)(C)C(OCC)=O.[H]Cl

Clinical Information

– Launched

Research Area

– Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– Adrenergic Receptor

Isoform

– α adrenergic receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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