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Methyldopate (hydrochloride)
SKU
HY-B1696A-25mg
Category Reference compound
Tags Adrenergic Receptor, Cardiovascular Disease, GPCR/G Protein;Neuronal Signaling
Products Details
Product Description
– Methyldopate hydrochloride is an ethyl ester hydrochloride proagent of α-Methyldopa (α-MD; HY-B0225). Methyldopa (L-(-)-α-Methyldopa) is an α-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopate hydrochloride has the potential for severe hypertension research[1].
Web ID
– HY-B1696A
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C12H18ClNO4
References
– [1]P D Walson, et al. Metabolic disposition and cardiovascular effects of methyldopate in unanesthetized rhesus monkeys. J Pharmacol Exp Ther. 1975 Oct;195(1):151-8.|[2]Hoskins JA, et al. Determination of alpha-methyldopa and methyldopate in human breast milk and plasma by ion-exchange chromatography using electrochemical detection. J Chromatogr. 1982 Jun 11;230(1):162-7.
CAS Number
– 2508-79-4
Molecular Weight
– 275.73
SMILES
– N[C@](CC1=CC=C(O)C(O)=C1)(C)C(OCC)=O.[H]Cl
Clinical Information
– Launched
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor
Isoform
– α adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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