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Products Details
Product Description
– Methyl tanshinonate is a tanshinone, that can be isolated from Salvia miltiorrhiza (S. miltiorrhiza) Bunge (Lamiaceae). Methyl tanshinonate is a potent inhibitor of Mpro enzyme in SARS-CoV (IC50 = 21.1 µM). Methyl tanshinonate can be used for diabetes and SARS-CoV research[1][2][3].
Web ID
– HY-126416
Shipping
– Room temperature
Molecular Formula
– C20H18O5
References
– [1]Kim DH, et al. Characterization of the inhibitory activity of natural tanshinones from Salvia miltiorrhiza roots on protein tyrosine phosphatase 1B. Chem Biol Interact. 2017 Dec 25;278:65-73.|[2]Ni L, et al. Qualitative analysis of the roots of Salvia miltiorrhiza and Salvia yunnanensis based on NIR, UHPLC and LC-MS-MS. J Pharm Biomed Anal. 2019 Jun 5;170:295-304.|[3]Diniz LRL, et al. Bioactive Terpenes and Their Derivatives as Potential SARS-CoV-2 Proteases Inhibitors from Molecular Modeling Studies. Biomolecules. 2021 Jan 7;11(1):74.
CAS Number
– 18887-19-9
Molecular Weight
– 338.35
SMILES
– O=C1C2=C(CCC[C@]3(C)C(OC)=O)C3=CC=C2C4=C(C(C)=CO4)C1=O
Clinical Information
– No Development Reported
Research Area
– Infection; Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
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