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Methyl pyropheophorbide-a
$90 – $720
Products Details
Product Description
– Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide-a has photodynamic activity and can induce apoptosis and inhibit tumor growth[1][2].
Web ID
– HY-137473
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C34H36N4O3
References
– [1]Sun X, et, al. Photodynamic therapy with pyropheophorbide-a methyl ester in human lung carcinoma cancer cell: efficacy, localization and apoptosis. Photochem Photobiol. 2002 Jun;75(6):644-51.|[2]Tian Y, et, al. Cell death induced by MPPa-PDT in prostate carcinoma in vitro and in vivo. Biochem Biophys Res Commun. 2006 Sep 22;348(2):413-20.
CAS Number
– 6453-67-4
Molecular Weight
– 548.67
Compound Purity
– 98.17
SMILES
– CC1=C(N2)/C=C(C(CC)=C3C)N=C3/C=C(C(C=C)=C/4C)NC4=C/C5=N/C([C@H]([C@@H]5C)CCC(OC)=O)=C(C6)C2=C1C6=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 2.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
