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Methyl ganoderate A acetonide
SKU
HY-N11641-Get quote
Category Natural Products
Tags Cholinesterase (ChE), Neurological Disease, Neuronal Signaling
Products Details
Product Description
– Methyl ganoderate A acetonide, a lanostane triterpene, is a natural product that could be isolated from the fruiting bodies of Ganoderma lucidum. Methyl ganoderate A acetonide is a potent AChE inhibitor with an IC50 value of 18.35 μM. Methyl ganoderate A acetonide can be used in research of Alzheimer’s disease (AD)[1].
Web ID
– HY-N11641
Shipping
– Room temperature
Molecular Formula
– C34H50O7
References
– [1]Lee I, et, al. Selective cholinesterase inhibition by lanostane triterpenes from fruiting bodies of Ganoderma lucidum. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6603-7.
CAS Number
– 1346453-53-9
Molecular Weight
– 570.76
SMILES
– C[C@@]12C3=C4[C@@]5([C@@](C(C)(C(CC5)=O)C)([H])C[C@]3([H])OC(C)(O[C@@]1([H])C[C@]([C@]2(CC4=O)C)([H])[C@H](C)CC(C[C@@H](C)C(OC)=O)=O)C)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– AChE
Pathway
– Neuronal Signaling
Product type
– Natural Products
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