Download Files:
Products Details
Product Description
– Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity[1].
Web ID
– HY-146165
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C13H11ClN2O4S
References
– [1]Li JQ, et, al. Hydroxamic acid with benzenesulfonamide: An effective scaffold for the development of broad-spectrum metallo-β-lactamase inhibitors. Bioorg Chem. 2020 Dec;105:104436.
CAS Number
– 1610537-25-1
Molecular Weight
– 326.76
SMILES
– O=C(NO)C1=CC=C(NS(=O)(C2=CC=C(Cl)C=C2)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
