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Products Details
Product Description
– Metallo-β-lactamase-IN-11 (compound 5f) is a Metallo-β-lactamases (MBLs) inhibitor, potent against bacterial metallophyllactamase CphA (IC50=45 µM). Metallo-β-lactamase-IN-11 (10 µM) inhibits NDM-1 by 49% and AIM-1 by 61%. Metallo-β-lactamase-IN-11 can be used in the research of inhibiting antibiotic resistance[1].
Web ID
– HY-155504
Shipping
– Room temperature
Molecular Formula
– C31H23N3O
References
– [1]Kurz JL, et al. Inhibitors for metallo-β-lactamases from the B1 and B3 subgroups provide an avenue to combat a major mechanism of antibiotic resistance. Bioorg Med Chem Lett. 2023 Jun 25;92:129387.
Molecular Weight
– 453.53
SMILES
– N#CC1=C(/N=C/C2=CC=C(O)C=C2)N(CC3=CC=CC=C3)C(C4=CC=CC=C4)=C1C5=CC=CC=C5
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
