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meta-iodoHoechst 33258
$420 – $2,520
Products Details
Product Description
– meta-iodoHoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
Web ID
– HY-15622
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H23IN6
References
– [1]Portugal J, Waring MJ. Assignment of DNA binding sites for 4′,6-diamidine-2-phenylindole and bisbenzimide (Hoechst 33258). A comparative footprinting study. Biochimica et Biophysica Acta 949 (2): 158-68.|[2]Latt SA, Stetten G, Juergens LA, Recent developments in the detection of deoxyribonucleic acid synthesis by 33258 Hoechst fluorescence. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 23 (7): 493-505.|[3]a b c “Hoechst Stains”. Invitrogren (Molecular Probes).
CAS Number
– 158013-42-4
Molecular Weight
– 534.39
Compound Purity
– 98.28
SMILES
– CN1CCN(C2=CC=C3N=C(C4=CC=C5N=C(C6=CC=CC(I)=C6)NC5=C4)NC3=C2)CC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : < 1 mg/mL (ultrasonic;warming;heat to 66°C)|Ethanol : 1 mg/mL (ultrasonic;warming)
Target
– DNA Stain
Pathway
– Cell Cycle/DNA Damage
Product type
– Dye Reagents
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
