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Mesyl Salvinorin B
SKU
HY-126910-500μg
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, Metabolic Disease, Opioid Receptor
$228
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Products Details
Product Description
– Mesyl Salvinorin B is a potent and selective kappa opioid receptor (KOP-r) agonist. Mesyl Salvinorin B prevents the ADE (Alcohol deprivation effect) in mice. Mesyl Salvinorin B dose-dependently reduces alcohol intake and preference in CED (chronic escalation drinking) mice[1][2].
Web ID
– HY-126910
Shipping
– Room temperature
Molecular Formula
– C22H28O9S
References
– [1]Zhou Y, et al. Effects of mesyl salvinorin B alone and in combination with naltrexone on alcohol deprivation effect in male and female mice. Neurosci Lett. 2018 Apr 23;673:19-23.|[2]Zhou Y, et al. Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone. Brain Res. 2017 May 1;1662:75-86.
CAS Number
– 862073-79-8
Molecular Weight
– 468.52
SMILES
– O=C([C@H](C[C@H](OS(=O)(C)=O)C([C@@]12[H])=O)[C@]1(C)CC[C@@]([C@]2(C)C[C@@H](C3=COC=C3)O4)([H])C4=O)OC
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Opioid Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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