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Meropenem (trihydrate)
SKU
HY-13678A-100 mg
Category Reference compound
Tags Anti-infection, Antibiotic;Bacterial, Infection; Cancer
$72 – $108
Products Details
Product Description
– Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2].
Web ID
– HY-13678A
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H31N3O8S
Citations
– Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00414-18. |Int J Antimicrob Agents. 2018 Aug;52(2):269-271.|Biomed Pharmacother. 2023 Nov 8:115856.|Infect Drug Resist. 2021 Jun 30;14:2499-2507.|J Antimicrob Chemother. 2020 Jul 1;75(7):1850-1858.|Nat Commun. 2022 Mar 2;13(1):1116.|Nat Microbiol. 2023 Mar;8(3):410-423.|Open Forum Infect Dis. 2023 Jan 27.|Spectrochim Acta A Mol Biomol Spectrosc. 2020 Apr 5;230:118066.
References
– [1]L Slaney, et al. In-vitro activity of meropenem against Neisseria gonorrhoeae, Haemophilus influenzae and H. ducreyi from Canada and Kenya. J Antimicrob Chemother. 1989 Sep;24 Suppl A:183-6.|[2]George G Zhanel, et al. Comparative review of the carbapenems. Drugs. 2007;67(7):1027-52.|[3]Umit Ateskan, et al. Deferoxamine and meropenem combination therapy in experimental acute pancreatitis. Pancreas. 2003 Oct;27(3):247-52.
CAS Number
– 119478-56-7
Molecular Weight
– 437.51
Compound Purity
– 99.92
SMILES
– O=C(C(N12)=C(S[C@@H]3CN[C@H](C(N(C)C)=O)C3)[C@H](C)[C@]2([H])[C@@H]([C@H](O)C)C1=O)O.O.O.O
Clinical Information
– Launched
Research Area
– Infection; Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 12.5 mg/mL (ultrasonic)
Target
– Antibiotic;Bacterial
Isoform
– β-lactam
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.