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Products Details
Product Description
– Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively[1].
Web ID
– HY-B0261A
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H12N3NaO4S2
References
– [1]Lazer ES, et al. Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity. J Med Chem. 1997 Mar 14;40(6):980-9.|[2]Iturriaga MP, et al. Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells. Oncol Lett. 2017 Aug;14(2):2198-2206.|[3]Fikry EM, et al. Rutin and meloxicam attenuate paw inflammation in mice: Affecting sorbitol dehydrogenase activity. J Biochem Mol Toxicol. 2018 Feb;32(2).
CAS Number
– 71125-39-8
Molecular Weight
– 373.38
SMILES
– O=C(C1=C(O[Na])C2=CC=CC=C2S(N1C)(=O)=O)NC3=NC=C(C)S3
Clinical Information
– Launched
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Autophagy;COX;MMP
Isoform
– COX-1;COX-2;MMP-2
Pathway
– Apoptosis;Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Reference compound
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