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Products Details
Product Description
– MEK-IN-6 (Example 69) is a MEK inhibitor. MEK-IN-6 inhibits ERK1/2 (Thr202/Tyr204) phosphorylation in A375 cells (IC50: 2 nM). MEK-IN-6 can be used for research of cancer[1].
Web ID
– HY-153445
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C18H20FN3O4S
References
– [1]Shelley Allen, et al. 3,4-dihydro-2,7-naphthyridine-1,6(2h,7h)-diones as mek inhibitors. Patent. WO2022208391.
CAS Number
– 2845151-86-0
Molecular Weight
– 393.43
SMILES
– O=C1C=C2C(C(N(CC2)OCCO)=O)=C(N1C)NC3=CC=C(C=C3F)SC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ERK;MEK
Isoform
– MEK
Pathway
– MAPK/ERK Pathway;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
