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Products Details
Product Description
– mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian α/β-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer[1].
Web ID
– HY-146696
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H17F6NOS
References
– [1]Bogdan Barnych, et al. Development of potent inhibitors of the human microsomal epoxide hydrolase. Eur J Med Chem. 2020 May 1;193:112206.
CAS Number
– 2418576-06-2
Molecular Weight
– 385.37
SMILES
– NC(C(C1CCCC1)SCC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Epoxide Hydrolase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
