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Mefenamic acid-13C6
SKU
HY-B0574S2-1mg
Category Isotope-Labeled Compounds
Tags COX;Isotope-Labeled Compounds, Immunology/Inflammation;Others, Inflammation/Immunology
Products Details
Product Description
– Mefenamic acid-13C6 is the 13C-labeled Mefenamic acid. Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively.
Web ID
– HY-B0574S2
Shipping
– Room temperature
Molecular Formula
– C9 13C6H15NO2
References
– [1]Gierse JK, et al. Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase. Biochem J. 1995 Jan 15;305 (Pt 2):479-84.|[2]Hashemipour MA, et al. In Vitro Cytotoxic Effects of Celecoxib, Mefenamic Acid, Aspirin and Indometacin on Several Cells Lines. J Dent (Shiraz). 2016 Sep;17(3):219-25.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1325559-19-0
Molecular Weight
– 247.24
SMILES
– OC([13C]([13CH]=[13CH][13CH]=[13CH]1)=[13C]1NC2=C(C(C)=CC=C2)C)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– COX;Isotope-Labeled Compounds
Pathway
– Immunology/Inflammation;Others
Product type
– Isotope-Labeled Compounds
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