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Products Details
Product Description
– Mechercharmycin A is a cytotoxic substance isolated from marine-derived Thermoactinomyces sp. YM3-251. Mechercharmycin A exhibits relatively strong antitumor activity[1][2].
Web ID
– HY-136293
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C35H32N8O7S
References
– [1]Kanoh K, et, al. Mechercharmycins A and B, cytotoxic substances from marine-derived Thermoactinomyces sp. YM3-251. J Antibiot (Tokyo). 2005 Apr;58(4):289-92.|[2]Hernández D, et, al. Synthesis and antitumor activity of mechercharmycin A analogues. J Med Chem. 2008 Sep 25;51(18):5722-30.
CAS Number
– 822520-96-7
Molecular Weight
– 708.74
SMILES
– O=C(N[C@](C(N[C@H](C(NC(C1=NC2=CO1)=C)=O)C(C)C)=O)([H])[C@@H](C)CC)C3=C(C4=CC=CC=C4)OC(C5=COC(C6=CSC(C7=COC2=N7)=N6)=N5)=N3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Natural Products
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