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ME0328
$60 – $610
Products Details
Product Description
– ME0328 is a potent and selective ARTD3/PARP3 inhibitor with an IC50 of 0.89±0.28 μM.
Web ID
– HY-100225
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H19N3O2
References
– [1]Lindgren AE, et al. PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3. ACS Chem Biol. 2013 Aug 16;8(8):1698-703.
CAS Number
– 1445251-22-8
Molecular Weight
– 321.37
Compound Purity
– 99.87
SMILES
– O=C(N[C@H](C1=CC=CC=C1)C)CCC(NC2=C3C=CC=C2)=NC3=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 75 mg/mL (ultrasonic)
Target
– PARP
Isoform
– PARP1;PARP10;PARP2;PARP3;TNKS1/PARP5A;TNKS2/PARP5B
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
